Product Detail
Product NameSTX1A Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityMouse,Rat
Immunogen DescA synthetic peptide of human STX1A
ConjugateUnconjugated
Other NamesSTX1A;HPC-1;P35-1;STX1;SYN1A;syntaxin-1A
Accession NoSwiss Prot:Q16623
GeneID:6804
Uniprot
Q16623
Calculated MW28kDa/29kDa/33kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded mouse kidney using STX1A (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using STX1A (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using STX1A (40x lens).
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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