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WHSC1 Rabbit Polyclonal Antibody#55381

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Product Detail

Product NameWHSC1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse

Immunogen DescRecombinant fusion protein of human WHSC1 (NP_579877.1).

ConjugateUnconjugated

Other NamesNSD2;KMT3F;KMT3G;MMSET;REIIBP;TRX5;WHS;WHSC1

Accession NoSwiss Prot:O96028
GeneID:7468

Uniprot O96028

Calculated MW30kDa/53kDa/66kDa/69kDa/71kDa/80kDa/152kDa

Sdspage MW80kDa, 152kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using WHSC1 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded mouse lung using WHSC1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using WHSC1 at dilution of 1:100 (40x lens).
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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