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ARHGEF11 Rabbit Polyclonal Antibody#55390

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Product Detail

Product NameARHGEF11 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse

Immunogen DescA synthetic peptide of human ARHGEF11

ConjugateUnconjugated

Other NamesARHGEF11;GTRAP48;PDZ-RHOGEF

Accession NoSwiss Prot:O15085
GeneID:9826

Uniprot O15085

Calculated MW167kDa/172kDa

Sdspage MW168kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Western blot analysis of extracts of mouse brain, using ARHGEF11 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human prostate cancer using ARHGEF11 (40x lens).
Immunohistochemistry of paraffin-embedded human lung using ARHGEF11 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using ARHGEF11 (40x lens).
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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