Product Detail
Product NameFZD4 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human FZD4 (NP_036325.2).
ConjugateUnconjugated
Other NamesFZD4;CD344;EVR1;FEVR;FZD4S;Fz-4;Fz4;FzE4;GPCR;hFz4
Accession NoSwiss Prot:Q9ULV1
GeneID:8322
Uniprot
Q9ULV1
Calculated MW59kDa
Sdspage MW70kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using FZD4 at 1:1000 dilution.
Western blot analysis of extracts of Rat kidney, using FZD4 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded mouse heart using FZD4 at dilution of 1:100 (40x lens).
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
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