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Location： Home > Polyclonal Antibodies > CD163 Rabbit Polyclonal Antibody

CD163 Rabbit Polyclonal Antibody#55495

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Product Detail

Product NameCD163 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human CD163 (NP_004235.4).

ConjugateUnconjugated

Other NamesCD163;M130;MM130;SCARI1

Accession NoUniprot:Q86VB7
GeneID:9332

Uniprot Q86VB7

Gene ID 9332

Calculated MW121kDa/124kDa/125kDa

Sdspage MW150KDa/160KDa

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:1000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of Rat liver, using CD163 antibody.
Western blot analysis of extracts of HepG2 cells, using CD163 antibody.
Immunohistochemistry of paraffin-embedded human liver using CD163 Rabbit pAb.
Immunofluorescence analysis of Raw264 7 cells using CD163 Rabbit pAb.
Immunofluorescence analysis of THP-1 cells using CD163 Rabbit pAb.
Western blot analysis of extracts of Mouse spleen, using CD163 antibody.
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

If you have published an article using product 55495, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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