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PER1 Rabbit Polyclonal Antibody#55519

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Product Detail

Product NamePER1 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

Immunogen DescRecombinant fusion protein of human PER1 (NP_002607.2).

ConjugateUnconjugated

Other NamesPER1;PER;RIGUI;hPER

Accession NoSwiss Prot:O15534
GeneID:5187

Uniprot O15534

Calculated MW91kDa/136kDa

Sdspage MW160kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using PER1 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human stomach using PER1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using PER1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse stomach using PER1 at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using PER1 at dilution of 1:100. Blue: DAPI for nuclear staining.
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

If you have published an article using product 55519, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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