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PRDM2 Rabbit Polyclonal Antibody#55542

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Product Detail

Product NamePRDM2 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityRat

Immunogen DescRecombinant fusion protein of human PRDM2 (NP_036363.2).

ConjugateUnconjugated

Other NamesPRDM2;HUMHOXY1;KMT8;KMT8A;MTB-ZF;RIZ;RIZ1;RIZ2

Accession NoSwiss Prot:Q13029
GeneID:7799

Uniprot Q13029

Calculated MW25kDa/162kDa/166kDa/184kDa/188kDa

Sdspage MW250kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of rat heart, using PRDM2 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat lung using PRDM2 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat liver using PRDM2 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat testis using PRDM2 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using PRDM2 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using PRDM2 at dilution of 1:100 (40x lens).
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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