Product Detail
Product NameNUP133 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman
Immunogen DescRecombinant fusion protein of human NUP133 (NP_060700.2).
ConjugateUnconjugated
Other NamesNUP133;hNUP133
Accession NoSwiss Prot:Q8WUM0
GeneID:55746
Uniprot
Q8WUM0
Calculated MW128kDa
Sdspage MW133kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:1000 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using NUP133 at 1:1000 dilution.
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.
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