Product Detail
Product NameC1QC Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman
Immunogen DescA synthetic peptide of human C1QC (NP_001107573.1).
ConjugateUnconjugated
Other NamesC1QC;C1Q-C;C1QG
Accession NoSwiss Prot:P02747
GeneID:714
Uniprot
P02747
Calculated MW25kDa
Sdspage MW26kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Western blot analysis of extracts of human serum, using C1QC at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human lung using C1QC at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using C1QC at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using C1QC at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using C1QC at dilution of 1:100 (40x lens).
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
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