Product Detail
Product NameNUMB Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human NUMB (NP_003735.3).
ConjugateUnconjugated
Other NamesNUMB;C14orf41;S171;c14_5527
Accession NoUniprot:P49757
GeneID:8650
Uniprot
P49757
Gene ID
8650
Calculated MW37kDa/48-70kDa
Sdspage MW71KDa
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using NUMB antibody.
Immunohistochemistry of paraffin-embedded mouse kidney using NUMB Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat kidney using NUMB Rabbit pAb.
Immunofluorescence analysis of L929 cells using NUMB antibody.
Immunohistochemistry of paraffin-embedded human liver using NUMB Rabbit pAb.
Immunohistochemistry of paraffin-embedded human lung cancer using NUMB Rabbit pAb.
Western blot analysis of extracts of various cell lines, using NUMB antibody.
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.
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