Product Detail
Product NameHACE1 Rabbit Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
Immunogen DescA synthetic peptide of human HACE1 (NP_065822.2).
ConjugateUnconjugated
Other NamesHACE1;SPPRS
Accession NoSwiss Prot:Q8IYU2
GeneID:57531
Uniprot
Q8IYU2
Calculated MW35kDa/63kDa/77kDa/102kDa
Sdspage MW102kDa
FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using HACE1 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human colon using HACE1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver cancer using HACE1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human placenta using HACE1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat testis using HACE1 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using HACE1 at dilution of 1:100 (40x lens).
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor.
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