Product Detail
                                
                                                                        Product NameHistone H2A.1 Rabbit Polyclonal Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC
                                        Species ReactivityHuman,Mouse,Rat
                                                                                                                         Immunogen DescRecombinant fusion protein of human Histone H2A.1 (NP_064707.1).
                                                                                 ConjugateUnconjugated
                                                                                 Other NamesHIST1H2AI;H2A/c;H2AFC
                                        Accession NoSwiss Prot:P0C0S8
Gene ID:8329
                                        Uniprot
                                        P0C0S8
                                        
                                        Gene ID
                                        8329
                                        
                                        Calculated MW14kDa
                                        Sdspage MW14kDa
                                                                                 FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:2000 - 1:5000
IHC	1:50 - 1:200
                             
                            
                                                                
                                    
                                    Western blot analysis of extracts of various cell lines, using Histone H2A.1 Antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded rat kidney using Histone H2A.1 antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human stomach using Histone H2A.1 antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded mouse heart using Histone H2A.1 antibody.
                                 
                                                             
                            
                                Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. 
                            
                            
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