Product Detail
                                
                                                                        Product NameHIST1H2BG Rabbit Polyclonal Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                        IsotypeIgG
                                        PurificationAffinity purification
                                        ApplicationsWB,IHC,IF
                                        Species ReactivityHuman,Mouse,Rat
                                                                                                                         Immunogen DescRecombinant protein of human HIST1H2BG
                                                                                 ConjugateUnconjugated
                                                                                 Other NamesHIST1H2BG;H2B.1A;H2B/a;H2BFA
                                        Accession NoSwiss Prot:P62807
Gene ID:8339
                                        Uniprot
                                        P62807
                                        
                                        Gene ID
                                        8339
                                        
                                        Calculated MW13kDa
                                        Sdspage MW14kDa
                                                                                 FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
                                        StorageStore at -20˚C. Avoid freeze / thaw cycles.
                                                                                                                                                         
                                Application Details
                                WB	1:500 - 1:2000
IHC	1:50 - 1:200
IF	1:50 - 1:200
                             
                            
                                                                
                                    
                                    Western blot analysis of extracts of various cell lines, using HIST1H2BG antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded human oophoroma using Histone H2B type 1-C\E\F\G\I antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded rat brain using Histone H2B type 1-C\E\F\G\I antibody.
                                 
                                                                
                                    
                                    Immunohistochemistry of paraffin-embedded mouse kidney using Histone H2B type 1-C\E\F\G\I antibody.
                                 
                                                                
                                    
                                    Immunofluorescence analysis of U-2 OS cells using Histone H2B type 1-C\E\F\G\I antibody.
                                 
                                                             
                            
                                Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein has antibacterial and antifungal antimicrobial activity. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. 
                            
                            
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