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SOCS6 Rabbit Polyclonal Antibody#55640

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Product Detail

Product NameSOCS6 Rabbit Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse

Immunogen DescRecombinant fusion protein of human SOCS6 (NP_004223.2).

ConjugateUnconjugated

Other NamesSOCS6;CIS-4;CIS4;HSPC060;SOCS-4;SOCS-6;SOCS4;SSI4;STAI4;STATI4

Accession NoSwiss Prot:O14544
GeneID:9306

Uniprot O14544

Calculated MW59kDa

Sdspage MW70kDa

FormulationBuffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using SOCS6 at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded human mammary cancer using SOCS6 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver cancer using SOCS6 at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using SOCS6 at dilution of 1:100 (40x lens).
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

If you have published an article using product 55640, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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