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Location： Home > Recombinant Rabbit Monoclonal Antibodies > Presenilin 1 Rabbit mAb

Presenilin 1 Rabbit mAb#59665

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Product Detail

Product NamePresenilin 1 Rabbit mAb

Host SpeciesRabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity-chromatography

ApplicationsWB FC

Species ReactivityHuman Mouse Rat

SpecificityPresenilin 1 Antibody detects endogenous levels of total Presenilin 1

Immunogen DescA synthesized peptide derived from human Presenilin 1

Other NamesAD3; Ad3h; FAD; Protein S182; PS1-CTF12; PSEN1; PSNL1; S182;

Accession NoUniprot:P49768

Uniprot P49768

FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Application Details
WB 1:500~1:2000 FC 1:10
Western blot analysis of Presenilin 1 expression in Jurkat cell lysate.
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.

If you have published an article using product 59665, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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