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TDP43 Rabbit mAb#60066

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Product Detail

Product NameTDP43 Rabbit mAb

Host SpeciesRabbit

ClonalityMonoclonal

IsotypeRabbit IgG

PurificationAffinity-chromatography

ApplicationsWB IHC ICC/IF FC

Species ReactivityHuman Mouse Rat

SpecificityTDP43 Antibody detects endogenous levels of total TDP43

Immunogen DescA synthesized peptide derived from TDP43

Other NamesALS10; TAR DNA binding protein 43; TARDBP; TDP43;

Accession NoUniprot:Q13148

Uniprot Q13148

Calculated MW45kDa

FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Application Details
WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
Western blot analysis of TDP43 expression in (1) HeLa cell lysate; (2) Mouse brain lysate; (3) Rat brain lysate.
Immunohistochemical analysis of paraffin-embedded human glioma, using TDP43 Antibody.
Immunofluorescent analysis of Hela cells, using TDP43 Antibody .
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis.

If you have published an article using product 60066, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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