Product Detail
Product NameFDPS Rabbit mAb
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeRabbit IgG
PurificationAffinity-chromatography
ApplicationsWB IHC
Species ReactivityHuman
SpecificityFDPS Antibody detects endogenous levels of total FDPS
Immunogen DescA synthesized peptide derived from human FDPS
Other NamesFarnesyl diphosphate synthase; Fdps; FPP synthase; FPP synthetase; FPPS; FPS; Geranyltranstransferase;
Accession NoUniprot:P14324
Uniprot
P14324
Calculated MWPredicted band size: 48 kDa
Sdspage MWObserved band size: 38 kDa
FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Application Details
WB: 1:500-1:2000
IHC: 1:50-1:200
All lanes: FDPS Rabbit mAb at 1/1k dilution
Lane 1 : HepG2 whole cell lysates
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) at 1/20000 dilution
Predicted band size: 48 kDa
Observed band size: 38 kDa
Exposure time: 4 seconds
All lanes:FDPS Rabbit mAb at 1/1k dilution
Lane 1 : Wild-type HAP1 cell lysate
Lane 2 :FDPS Rabbit mAb knockdown HAP1 cell lysate
Lysates/proteins at 20 µg per lane.
Formalin-fixed, paraffin-embedded human lung cancer tissue stained for FDPS using 60110 at 1/100 dilution in immunohistochemical analysis.
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones.
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