Product Detail
Product NameClusterin Rabbit mAb
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeRabbit IgG
PurificationAffinity-chromatography
ApplicationsWB IHC IP
Species ReactivityMouse Rat
SpecificityClusterin Antibody detects endogenous levels of total Clusterin
Immunogen DescA synthesized peptide derived from human Clusterin
ConjugateUnconjugated
Other NamesAAG4; Aging-associated gene 4 protein; APOJ; ApoJalpha; ApoJbeta; Apolipoprotein J; CLI; CLU; Clusterin alpha chain; Clusterin; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor; Complement cytolysis inhibitor b chain; complement lysis inhibitor; Ku70-binding protein 1; KUB1; NA1/NA2; SGP2; sulfated glycoprotein 2; Testosterone-repressed prostate message 2; TRPM2;
Accession NoUniprot:Q06890(mouse)
Uniprot
Q06890(mouse)
FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Application Details
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Western blot analysis of Clusterin expression in mouse serum cell lysate.
Isoform 1:Functions as extracellular chaperone that prevents aggregation of non native proteins (PubMed:11123922, PubMed:19535339).Prevents stress-induced aggregation of blood plasma proteins (PubMed:11123922, PubMed:12176985, PubMed:17260971, PubMed:19996109).Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro) (PubMed:12047389, PubMed:17412999, PubMed:17407782).
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