Product Detail
Product NamePDE8B Antibody
Host SpeciesRabbit
ClonalityPolyclonal
Purificationaffinity purified by Protein A
ApplicationsIHC;ICC/IF
Species Reactivity(predicted: Human, Mouse, Rat)
SpecificityThe antibody detects endogenous level of total PDE8B protein
Immunogen TypePeptide
Immunogen DescKLH conjugated synthetic peptide derived from human PDE8B
Uniprot
O95263;
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
IHC 1:100-500;ICC/IF 1:100-500
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
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Yes
