Product Detail
Product NameHHV8 antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity purified by Protein A.
ApplicationsIHC-P, IHC-F, IF, ICC/IF, ELISA
Species ReactivityHHV8
Immunogen TypePeptide
Immunogen Descpeptide derived from HHV8 ORF8: 501-600/845
Target NameHHV8
Uniprot
F5HB81
Gene ID
4961501
Calculated MW92kDa
Concentration1mg/ml
FormulationLiquid in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at +4˚C for short term. Store at -20˚C for long term. Avoid freeze/thaw cycle.
Application Details
IHC-P 1:100-500, IHC-F 1:100-500, IF 1:100-500, ICC/IF 1:100-500, ELISA 1:5000-10000
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
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