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Location： Home > Polyclonal Antibodies > Matriptase 2 antibody

Matriptase 2 antibody#62150

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Product Detail

Product NameMatriptase 2 antibody

Host SpeciesRabbit

ClonalityPolyclonal

Purificationaffinity purified by Protein A

ApplicationsIHC, IF

Species ReactivityRat Human, Mouse

Immunogen DescKLH conjugated synthetic peptide derived from human Matriptase 2: 711-811/811

Target NameMatriptase2

Uniprot Q8IU80

Gene ID 164656

Calculated MW89 kDa

Concentration1mg/ml

Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

Application Details
IHC-P 1:100-500, IHC-F 1:100-500, IF 1:100-500
Immunohistochemical analysis of paraffin-embedded rat liver with Matriptase 2 antibody at 1:200.
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

If you have published an article using product 62150, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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