Product Detail
                                
                                                                        Product NameETBR Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                                                                PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
                                        ApplicationsWB;IHC;IF
                                        Species ReactivityHuman; Mouse; Rat
                                        SpecificityThe antibody detects endogenous level of total ETBR protein.
                                        Immunogen TypePeptide
                                         Immunogen DescSynthesized peptide derived from ETBR at AA range: 31-80
                                         Target NameETBR
                                         ConjugateUnconjugated
                                                                                                                                                                Uniprot
                                        P24530
                                        
                                        Gene ID
                                        1910
                                        
                                        Calculated MW50kDa
                                                                                Concentration1mg/ml
                                         FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
                                        StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
                                                                                                                                                         
                                Application Details
                                IHC: 100-300; WB 1:500-2000; IF 1:50-200
                             
                            
                                                                
                                    
                                    All lanes : ETBR Antibody at 1/500 dilutionLane 1 : Hela whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryAll lanes : Goat Anti-Rabbit IgG H&L (HRP) at 1/20000 dilution
Predicted band size: 50 kDa Observed band size: 50 kDaExposure time: 3 seconds
                                 
                                                                
                                    
                                    Formalin-fixed, paraffin-embedded human-placenta tissue stained for ETBR at 1/200 dilution in immunohistochemical analysis.
                                 
                                                                
                                    
                                    Formalin-fixed, paraffin-embedded Human placenta tissue stained for ETBR  at 1/200 dilution in immunohistochemical analysis.
                                 
                                                             
                            
                                The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],
                            
                            
                                If you have published an article using product 62213, please notify us so that we can cite your literature.