Product Detail
Product NameTBX19 Mouse mAb
Clone No.MR4519
Host SpeciesMouse
ClonalityMonoclonal
IsotypeIgG1
PurificationPurified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
ApplicationsWB,IHC
Species ReactivityHuman,Mouse
Immunogen Typeprotein
Immunogen DescHuman recombinant protein fragment corresponding to amino acids 1-238 of human TBX19 (NP_005140) produced in E.coli.
Target NameTBX19
Other NamesT-box factor, pituitary
Uniprot
O60806
Gene ID
9095
Calculated MW48KD
FormulationPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% New type preservative N.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Application Details
WB 1:1000-1:2000
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TBX19 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TBX19.
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]
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