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Recombinant Human Vascular cell adhesion protein 1(VCAM1),partial#AP70908

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Product Detail

Product NameRecombinant Human Vascular cell adhesion protein 1(VCAM1),partial

Host SpeciesE.coli

PurificationGreater than 90% as determined by SDS-PAGE.

Immunogen DescExpression Region:25-698aa
Sequence Info:Extracellular Domain

Other NamesINCAM-100; CD106

Accession NoP19320

Uniprot P19320

Gene ID 7412;

Calculated MW90.2 kDa

FormulationTris-based buffer50% glycerol

StorageThe shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20˚C,-80˚C. The shelf life of lyophilized form is 12 months at -20˚C,-80˚C.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4˚C for up to one week.

Tag InfoN-terminal 6xHis-SUMO-tagged

Application Details
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4,beta-1 (ITGA4,ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1,ITGA4,ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte igration to sites of inflammation.

If you have published an article using product AP70908, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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