Product Detail
Product NameSLC1A5 Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
Applications IF
Species ReactivityHu
Immunogen DescKLH conjugated synthetic peptide aa 460-504 504 derived from human SLC1A5
Target NameSLC1A5
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesR16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1; Neutral amino acid transporter B(0); ATB(0); Baboon M7 virus receptor; RD114 simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5; SLC1A5; RDR
Accession NoSwiss-Prot#Q15758
NCBI Gene ID6510
Uniprot
Q15758
Gene ID
6510;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
IF=1:50-200
Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1 ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
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