Product Detail
Product NameCD18 Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsICC IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 724-769 769 derived from human Integrin beta 2
Target NameCD18
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesLAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; Integrin beta-2; Cell surface adhesion glycoproteins LFA-1 CR3 p150,95 subunit beta; Complement receptor C3 subunit beta; ITGB2
Accession NoSwiss-Prot#P05107
NCBI Gene ID3689
Uniprot
P05107
Gene ID
3689;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
ICC=1:50-200 IF=1:50-200
Integrin alpha-L beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M beta-2 and alpha-X beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M beta-2 is also a receptor for factor X. Integrin alpha-D beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B PYK2-mediated activation.
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