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Integrin alpha 4 CD49d Antibody FITC Conjugated#C00368F

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Product Detail

Product NameIntegrin alpha 4 CD49d Antibody FITC Conjugated

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationPurified by Protein A.

ApplicationsFCM IF(IHC-P)

Species ReactivityHu Ms Rt Rb

Immunogen DescKLH conjugated synthetic peptide aa 584-609 1032 derived from human Integrin alpha 4

Target NameIntegrin alpha 4 CD49d

ConjugateFITC

Excitation Emission494nm 518nm

Other NamesIA4; CD49D; Integrin alpha-4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; ITGA4

Accession NoSwiss-Prot#P13612
NCBI Gene ID3676

Uniprot P13612

Gene ID 3676;

Concentration1mg ml

Formulation10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Store at 4C for 12 months.

Application Details
FCM: 1:20-100
Immunofluorescence: 1:50-200
Integrins alpha-4 beta-1 (VLA-4) and alpha-4 beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4 beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4 beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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