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Location: Home > Conjugated Antibodies > Angiopoietin 2 Antibody HRP Conjugated

Angiopoietin 2 Antibody HRP Conjugated#C00392H

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Product Detail

Product NameAngiopoietin 2 Antibody HRP Conjugated

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationPurified by Protein A.

ApplicationsWB IHC-P IHC-F

Species ReactivityHu Ms Rt

Immunogen DescKLH conjugated synthetic peptide aa 450-490 496 derived from human Angiopoietin 2

Target NameAngiopoietin 2

ConjugateHRP

Excitation EmissionN A

Other NamesANG2; AGPT2; Angiopoietin-2; ANG-2; ANGPT2

Accession NoSwiss-Prot#O15123
NCBI Gene ID285

Uniprot O15123

Gene ID 285;

Concentration1mg ml

Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200
Binds to TEK TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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