Product Detail
Product NameE cadherin Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
Applications ICC IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 410-460 882 derived from human E-cadherin
Target NameE cadherin
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesUVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12 8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
Accession NoSwiss-Prot#P12830
NCBI Gene ID999
Uniprot
P12830
Gene ID
999;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
ICC=1:50-200 IF=1:50-200
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E beta-7. E-Cad CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
If you have published an article using product C00534F, please notify us so that we can cite your literature.
15 business days.
