Product Detail
Product NameE cadherin Antibody HRP Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsWB IHC-P IHC-F ICC
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 410-460 882 derived from human E-cadherin
Target NameE cadherin
ConjugateHRP
Excitation EmissionN A
Other NamesUVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12 8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1
Accession NoSwiss-Prot#P12830
NCBI Gene ID999
Uniprot
P12830
Gene ID
999;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E beta-7. E-Cad CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
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15 business days.
