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CD11b/PE Conjugated antibody#C00620P

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Product Detail

Product NameCD11b/PE Conjugated antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationPurified by Protein A.

ApplicationsFCM IF

Species ReactivityHu Ms Rt

Immunogen DescKLH conjugated synthetic peptide aa 50-100 1152 derived from human CD11b

Target NameCD11b, CD11c

ConjugatePE

Excitation Emission480,565nm 578nm

Other NamesCR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6; Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; ITGAM

Accession NoSwiss-Prot#P11215
NCBI Gene ID3684

Uniprot P11215

Gene ID 3684;

Concentration1mg ml

Formulation10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Store at 4C for 12 months.

Application Details

FCM: 1:20-100

IF=1:50-200

Integrin alpha-M beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

If you have published an article using product C00620P, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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