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Location: Home > Conjugated Antibodies > GADD34 Antibody FITC Conjugated

GADD34 Antibody FITC Conjugated#C00686F

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Product Detail

Product NameGADD34 Antibody FITC Conjugated

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationPurified by Protein A.

ApplicationsFlow-Cyt,ICC,IF

Species ReactivityHu Ms Rt

Immunogen DescKLH conjugated synthetic peptide aa 415-450 674 derived from human GADD34

Target NameGADD34

ConjugateFITC

Excitation Emission494nm 518nm

Other NamesGADD34; Protein phosphatase 1 regulatory subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog; PPP1R15A

Accession NoSwiss-Prot#O75807
NCBI Gene ID23645

Uniprot O75807

Gene ID 23645;

Concentration1mg ml

Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.

Application Details
Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
Recruits the serine threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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