Product Detail
Product NameCD86 Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsFlow-Cyt,ICC,IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 130-180 313 derived from rat CD86
Target NameCD86
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesB7-2, Cd86 antigen; Cd86; Membrane glycoprotein
Accession NoSwiss-Prot#O35531
NCBI Gene ID56822
Uniprot
O35531
Gene ID
56822;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
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