Product Detail
Product NameGPM6A Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsFlow-Cyt,ICC,IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 160-200 278 derived from human GPM6A
Target NameGPM6A
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesM6A; GPM6; Neuronal membrane glycoprotein M6-a; GPM6A
Accession NoSwiss-Prot#P51674
NCBI Gene ID2823
Uniprot
P51674
Gene ID
2823;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
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15 business days.
