Product Detail
Product NamePAX6 Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsFlow-Cyt,ICC,IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 54-103 422 derived from human PAX6
Target NamePAX6
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesAN; AN2; FVH1; MGDA; WAGR; D11S812E; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6
Accession NoSwiss-Prot#P26367
NCBI Gene ID5080
Uniprot
P26367
Gene ID
5080;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
Flow-Cyt=2ug/Test ICC=1:50-200 IF=1:50-200
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
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15 business days.
