Product Detail
Product NameSema4C Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsIF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide derived from human Sema4C
Target NameSema4C
ConjugateFITC
Excitation Emission494nm 518nm
Other NamessemF; SEMAF; Semaphorin-5A; Semaphorin-F; Sema F; SEMA5A
Accession NoSwiss-Prot#Q13591
NCBI Gene ID9037
Uniprot
Q13591
Gene ID
9037;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
IF=1:50-200
Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
If you have published an article using product C01043F, please notify us so that we can cite your literature.
15 business days.
