Product Detail
Product NameArginase II Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsICC,IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 180-230 354 derived from human Arginase II
Target NameArginase II
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesArginase-2, mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase; ARG2
Accession NoSwiss-Prot#P78540
NCBI Gene ID384
Uniprot
P78540
Gene ID
384;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
ICC=1:50-200 IF=1:50-200
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
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