Product Detail
Product NameAANAT (Phospho-Thr29) Antibody HRP Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsWB,,IHC-P,IHC-F,ICC
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic phosphopeptide derived from mouse AANAT around the phosphorylation site of Thr29
Target NameAANAT Thr29
ConjugateHRP
Excitation EmissionN A
Other Namesp-AANATThr29; p-AANATT29; AANATphospho Thr29; p-AANATT29
Accession No
NCBI Gene ID11298
Uniprot
O88816
Gene ID
11298;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep wake cycle.
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