Product Detail
Product NameCRBN Antibody PE Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsFCM
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide derived from human CRBN
Target NameCRBN
ConjugatePE
Excitation Emission480,565nm 578nm
Other NamesCereblon; DKFZp781K0715; MGC27358; MRT2A; OTTHUMP00000209555; piL; Protein cereblon; Protein x 0001; 2610203G15Rik; 2900045O07Rik; AF229032; AW108261; CRBN_HUMAN.
Concentration1mg ml
Formulation10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Store at 4C for 12 months.
Application Details
FCM: 1:20-100
CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
If you have published an article using product C01432P, please notify us so that we can cite your literature.
15 business days.
