Product Detail
Product NameAcetyl Coenzyme A Carboxylase alpha (Phospho-Ser80) Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsICC IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser80
Target NameAcetyl Coenzyme A Carboxylase alpha Ser80
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesAcetyl Coenzyme A Carboxylase alpha phospho S80; p-Acetyl Coenzyme A Carboxylase alpha phospho S80; ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC; ACC-alpha; ACC1; ACC1; ACCA; acetyl CoA carboxylase 1; acetyl Coenzyme A; Acetyl Coenzyme A; Biotin carboxylase; Acetyl-Coenzyme A Carboxylase alpha.
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
ICC=1:50-200 IF=1:50-200
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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