Product Detail
Product NameCCR7 CD197 Antibody PE Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsFCM
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 25-59 379 derived from mouse CCR7
Target NameCCR7 CD197
ConjugatePE
Excitation Emission480,565nm 578nm
Other NamesEBI1; CCR-7; CD197; Ebi1h; Cdw197; Cmkbr7; CC-CKR-7; C-C chemokine receptor type 7; C-C CKR-7; Epstein-Barr virus-induced G-protein coupled receptor 1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; Ccr7
Accession NoSwiss-Prot#P47774
NCBI Gene ID12775
Uniprot
P47774
Gene ID
12775;
Concentration1mg ml
Formulation10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Store at 4C for 12 months.
Application Details
FCM: 1:20-100
CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19 ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.
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