Product Detail
Product NameShh Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsIF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 20-70 462 derived from human Shh
Target NameShh
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesTPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; Sonic hedgehog protein; SHH; HHG-1
Accession NoSwiss-Prot#Q15465
NCBI Gene ID6469
Uniprot
Q15465
Gene ID
6469;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
IF=1:50-200
Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
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15 business days.
