Product Detail
Product NameCLEC16A Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsICC IF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 760-795 1053 derived from human CLEC16A
Target NameCLEC16A
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesGop-1; KIAA0350; Protein CLEC16A; C-type lectin domain family 16 member A; CLEC16A
Accession NoSwiss-Prot#Q2KHT3
NCBI Gene ID23274
Uniprot
Q2KHT3
Gene ID
23274;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
ICC=1:50-200 IF=1:50-200
Regulator of mitophagy through the upstream regulation of the RNF41 NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41 NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41 NRDP1 from proteosomal degradation, RNF41 NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy autophagy and mitochondrial health.
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