Product Detail
Product NameTNF alpha Antibody HRP Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsWB IHC-P IHC-F ICC
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 180-230 235 derived from mouse TNF-alpha
Target NameTNF alpha
ConjugateHRP
Excitation EmissionN A
Other NamesDIF; Tnfa; TNF-a; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha; Tumor necrosis factor; Cachectin; Tumor necrosis factor ligand superfamily member 2; Tnf
Accession NoSwiss-Prot#P06804
NCBI Gene ID21926
Uniprot
P06804
Gene ID
21926;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
Cytokine that binds to TNFRSF1A TNFR1 and TNFRSF1B TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
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15 business days.
