Product Detail
Product NameCD47 MER6 Antibody PE Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsFCM
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 280-323 323 derived from human CD47 MER6
Target NameCD47 MER6
ConjugatePE
Excitation Emission480,565nm 578nm
Other NamesIAP; OA3; MER6; Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; Protein MER6; CD47
Accession NoSwiss-Prot#Q08722
NCBI Gene ID961
Uniprot
Q08722
Gene ID
961;
Concentration1mg ml
Formulation10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Store at 4C for 12 months.
Application Details
FCM: 1:20-100
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
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