Product Detail
Product NameMuRF1 Trim63 Antibody FITC Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsIF
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 280-315 353 derived from human MuRF1 Trim63
Target NameMuRF1 Trim63
ConjugateFITC
Excitation Emission494nm 518nm
Other NamesMuRF 1; MuRF-1; Muscle-specic RING finger protein 1; Muscle-specic RING finger protein 1; E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; MURF1; MURF 1; MURF2; RNF28; SMRZ; Iris ring finger protein; Muscle specic ring finger protein 2; Ring finger protein 28; RNF28; SMRZ; Striated muscle RING zin
Accession No
NCBI Gene ID84676
Uniprot
Q969Q1
Gene ID
84676;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
IF=1:50-200
This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].
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