Product Detail
Product NameGPNMB Antibody HRP Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsWB IHC-P IHC-F
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 85-135 572 derived from human GPNMB
Target NameGPNMB
ConjugateHRP
Excitation EmissionN A
Other NamesNMB; HGFIN; Transmembrane glycoprotein NMB; Transmembrane glycoprotein HGFIN; GPNMB; UNQ1725 PRO9925
Accession NoSwiss-Prot#Q14956
NCBI Gene ID10457
Uniprot
Q14956
Gene ID
10457;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
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