Product Detail
Product NameHDAC4 Antibody HRP Conjugated
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by Protein A.
ApplicationsWB IHC-P IHC-F
Species ReactivityHu Ms Rt
Immunogen DescKLH conjugated synthetic peptide aa 130-180 1084 derived from human HDAC4
Target NameHDAC4
ConjugateHRP
Excitation EmissionN A
Other NamesHD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; Histone deacetylase 4; HDAC4; KIAA0288
Accession NoSwiss-Prot#P56524
NCBI Gene ID9759
Uniprot
P56524
Gene ID
9759;
Concentration1mg ml
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
StorageShipped at 4˚C. Store at -20˚C for one year. Avoid repeated freeze/thaw cycles.
Application Details
WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
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15 business days.
