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Conjugated PML Rabbit mAb#C56159

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Product Detail

Product NameConjugated PML Rabbit mAb

Host SpeciesRecombinant Rabbit

ClonalityMonoclonal

PurificationAffinity-chromatography

Species ReactivityHuman Mouse Rat

SpecificityPML Antibody detects endogenous levels of total PML

Immunogen DescA synthesized peptide derived from human PML

ConjugateAF Dye

Excitation EmissionAF350: 346nm/442nm;
AF405: 401nm/421nm;
AF488: 493nm/519nm;
AF555: 555nm/565nm;
AF594: 591nm/614nm;
AF647: 651nm/667nm;
AF680: 679nm/702nm;
AF750: 749nm/775nm;

Other NamesProtein PML; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19; MYL; PP8675; RNF71; TRIM19;

Accession NoUniprot:P29590

Uniprot P29590

Calculated MW48-120kDa

FormulationLiquid in PBS, 0.5% BSA, 40% Glycerol, 0.02% Sodium Azide.

StorageStore at 4˚Cin dark for 6 months

Application Details
Suggested Dilution:;
AF350 conjugated: most applications: 1: 50 - 1: 250;
AF405 conjugated: most applications: 1: 50 - 1: 250;
AF488 conjugated: most applications: 1: 50 - 1: 250;
AF555 conjugated: most applications: 1: 50 - 1: 250;
AF594 conjugated: most applications: 1: 50 - 1: 250;
AF647 conjugated: most applications: 1: 50 - 1: 250;
AF680 conjugated: most applications: 1: 50 - 1: 250;
AF750 conjugated: most applications: 1: 50 - 1: 250;
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000;
Regulates RB1 phosphorylation and activity. Required for normal development of the brain cortex during embryogenesis. Can sequester herpes virus and varicella virus proteins inside PML bodies, and thereby inhibit the formation of infectious viral particles. Regulates phosphorylation of ITPR3 and plays a role in the regulation of calcium homeostasis at the endoplasmic reticulum (By similarity). Regulates transcription activity of ELF4.

If you have published an article using product C56159, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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