Product Detail
Product NameHistone H3K4me1 Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen TypePeptide
Immunogen DescA synthetic methylated peptide of human histone H3
Target NameHistone H3
ConjugateUnconjugated
Other NamesH3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A
Accession NoUniprot:Q16695
GeneID:8290
Uniprot
Q16695
Gene ID
8290
Sdspage MW17KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MonoMethyl-Histone H3-K4 antibody.
Immunofluorescence analysis of U-2 OS cells using MonoMethyl-Histone H3-K4 antibody.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
If you have published an article using product HW001, please notify us so that we can cite your literature.
et al,Small molecule inhibitors of the prostate cancer target KMT2D. In Biochem Biophys Res Commun on 2020 Dec 10 by Qi Yu, Zonglang Liao, et al..PMID:32988590
, (2020),
PMID:
32988590
Yes
